2026
2025
Shunxi Dong, Xiaoming Feng, Xiaohua Liu,* Guanidine-Amide-Based Chiral Organocatalysts and Ligands for Asymmetric Catalysis. Acc. Chem. Res. 2025, 58, 3463–3479.
Weidi Cao, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Radical Reactions Enabled by Chiral N,N′‑Dioxide−Metal Complexes, Acc. Chem. Res. 2025, 58, 2496−2510.
Hongye Li, Zhiqiang Li, Aying Yihuo, Yuqiao Zhou, Sile Li, Xiaoming Feng,* Xiaohua Liu,* Enantioselective Radical Sulfonylation of 2-Naphthols and β-Ketoamides with Sodium Sulfinates. J. Am. Chem. Soc. 2025, 147, 10.1021/jacs.5c15392
Yu-Jia Chen,† Pengfei Xie,† Lei Zhang, Anzai Shi, Youai Qiu,* Qi-Lin Zhou,* Electroreduction of Aromatic Carboxylic Derivatives to Aldehydes, J. Am. Chem. Soc. 2025,147, 43737–43744.
Zhi-Peng Shi, Zi-Han Lin, Ye-Xuan Xu, Long-Fei Fan, Pu-Sheng Wang,* Xin Hong,* Liu-Zhu Gong,* Palladium-Catalyzed Site− and Enantiodifferentiating Allylic C−H Alkylation of Internal Alkenes, J. Am. Chem. Soc. 2025, 147, 42559–42571.
Jia Yang,† Longqing Yang,† Yuexin Zhao, Liuzhen Hou, Yong Qiu, Guihua Pan, Xiaohua Liu,* Xiaoming Feng,* Shunxi Dong,* Asymmetric Dearomative [2+2] Photocycloaddition of Quinoline and Indole Derivatives with Bicyclo[1.1.0]butanes, J. Am. Chem. Soc. 2025, 147, 35755–35766.
Ye-Wei Huang, Tianze Zhang, Shi-Hui Cheng, Qi-Lin Zhou, Li-Jun Xiao,* Nickel-Catalyzed Enantioselective Direct Addition of Styrenes to Imines Enabled by Chiral Spiro Phosphine Ligands, J. Am. Chem. Soc. 2025, 147, 35675–35683.
Xinlong Yan,† Zichun Zhang,† Zhenwei Wu, Fule Wu, Xiaoming Feng,* Yangbin Liu,* Stereodivergent Synthesis of Allylic All-Carbon Quaternary Centers by Bimetallic Iridium/Magnesium-Catalyzed Allylic Alkylation. J. Am. Chem. Soc. 2025, 147,34869−34880.
Zheng Wang, Li-Yuan Xue, Yue Xu, Qi-Lin Zhou,* Iridium-Catalyzed Asymmetric Hydrogenation of Aryl(4-hydroxyphenyl)ketones. J. Am. Chem. Soc. 2025, 147, 19491–19497.
Fu Li, Xian-Ming Liu, Jia-Bin Pan, Ling Dai, Yin Yang, Li-Jun Xiao, Chao Fan, Qi-Lin Zhou,* Photo- and Copper-Catalyzed Enantioselective Oxidation of Benzylic C(sp3)−H Bonds, J. Am. Chem. Soc. 2025, 147, 19093–19100.
Fule Wu,† Hongkai Wang,† Zhenwei Wu, Yangbin Liu,* Xiaoming Feng,* Solvent-Controlled Enantioselective Allylic C−H Alkylation of 2,5-Dihydrofuran via Synergistic Palladium/Nickel Catalysis, J. Am. Chem. Soc. 2025, 147, 16237−16247.
Ying-Ying Chen, Ling Dai, Xuan-Ge Zhang, Qi-Lin Zhou,* Copper-Catalyzed Enantioselective Three-Component Carboamidation of Styrenes with Alkanes and Amides. J. Am. Chem. Soc. 2025, 147, 12397–12404.
Kai Wang, Kai-Yuan Tian, Xin-Ning Wang, Jing-Hao Chen, Chao Fan, Qi-Lin Zhou*. Ligand Enabled Iridium-Catalyzed Enantioselective Hydroalkenylation of α-Olefins and Styrenes with Acrylamides. J. Am. Chem. Soc. 2025, 147, 11639–11646.
Xin-Yi Yang, Xuan-Ge Zhang, Qi-Lin Zhou,* Enantioselective Reduction of 1-Naphthamides by Electrochemical Reduction and Catalytic Asymmetric Hydrogenation in Tandem. J. Am. Chem. Soc. 2025, 147, 10052-10058.
Bin Qing,† Zhuang Yang,† Zhenwei Wu,† Zichun Zhang, Yuqiao Zhou, Xinlong Yan, Yangbin Liu,* Xiaoming Feng,* Stereodivergent Construction of 3,3′-Disubstituted Oxindoles via One-Pot Sequential Allylation/Alkylation and Its Application to the Total Synthesis of Trigolute B and D, J. Am. Chem. Soc. 2025, 147, 7729–7740.
Chang-Liang Zhu, Xueyuan Yan, Huai-Yu Bin, Xiong Wu, Zheng-Yan Huang, Pu-Cha Yan,* Genping Huang,* Jian-Hua Xie,* Qi-Lin Zhou, Enantioselective Synthesis of Chiral 1,4-Dihydroquinolines via Iridium-Catalyzed Asymmetric Partial Hydrogenation of Quinolines. J. Am. Chem. Soc. 2025, 147, 5725-5735.
Xian-Ming Liu, Fu Li, Tong-Kun Wang, Ling Dai, Yin Yang, Neng-Quan Jiang, Li-Yuan Xue, Jing-Yuan Liu, Xiao-Song Xue,* Li-Jun Xiao,* Qi-Lin Zhou,* Catalytic Asymmetric Oxidative Coupling between C(sp3)-H Bonds and Carboxylic Acids. J. Am. Chem. Soc. 2025, 147, 627-635.
Weiwei Xu, Yanan Sun,† Yuqing Jiang,† Xueyuan Yan, Zhixuan Gao, Haorui Wang, Genping Huang,* Qi-Lin Zhou, Mengchun Ye,* Enantioselective Carbonylative Cyclization of Alkenes with C−H Bonds for Synthesis of γ‑Lactams Bearing an α‑Quaternary Carbon, J. Am. Chem. Soc. 2025, 147, 96-103.
Zhendong Yang,† Maoping Pu,†Liangkun Yang, Yuqiao Zhou, Hongda Wu, Bosheng Wang, Xiaoming Feng,* Xiaohua Liu,* Metal-Controlled Enantiodivergent Tandem Rearrangement to Synthesize 2H-Azirines, Angew. Chem. Int. Ed. 2025, 64, e202505725.
Xiaofan Chen, Yuqiao Zhou, Ming Yang, Yuntian Yang, Xiaoming Feng,* Weidi Cao,* Merging Photocatalysis with Chiral Lewis Acid Catalysis for Enantioselective Hydrosilylation/Hydrogermylation of Electron-Deficient Alkenes. Angew. Chem. Int. Ed.2025, 64, e202504676.
Mingyi Jiang, Zengcheng Yu, Linhan Yang, Fei Wang, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Reductant-Free Enantioselective Aza-Reformatsky Reaction Enabled by Synergistic Visible Light Photocatalysis and Lewis Acid Catalysis, Angew. Chem. Int. Ed.2025, 64, e202500756.
Hongkai Wang, Lijuan Song, Jing Huang, Fule Wu, Zhuang Yang, Yangbin Liu,* Yun-Dong Wu,* Xiaoming Feng,* Regiodivergent and Enantioselective Allylic C−H Alkylation of Allyl Ethers: Optimization, Scope, Mechanism and Application, Angew. Chem. Int. Ed. 2025, 64, e202500125.
Shiyang Li, Shi Yan, Zhenzhong Liu, Yang Zhang, Yuqiao Zhou, Xiaoming Feng, Liang-Wen Feng,* Xiaohua Liu,* Enantioselective Homologation of Helical Architectures: From Fluorenones to Phenanthrenones with Enhanced Circular Dichroism. Nat. Commun. 2025, 16, 9083.
Xuqiang Guo, Xinwen Cui, Mingzhen Lu, Qi-Lin Zhou, Weiwei Xu* Mengchun Ye,* Photoexcited nitroarene-enabled carbon chain-elongated oxidation of alkenes via tandem oxidative cleavage and dipolar cycloaddition. Nat. Commun. 2025, 16, 4504.
Jiuqi Tan, Hanyu Su, Min Chen, Fengnan Xiao, Longqing Yang, Xiaoming Feng, Liang-Wen Feng*, Xiaohua Liu,* Asymmetric Cross-Dehydrogenative Coupling of Glycinates via Iodine-Mediated Photoredox/Lewis Acid Synergistic Catalysis, ACS Catalysis 2025, 15, 9633–9642.
Xian-Ming Liu. Fu Li. Li-Yuan Xue. Ling Dai. Jing-Yuan Liu. Li-Jun Xiao, Qi-Lin Zhou,* Copper-catalyzed Enantioselective Oxidative Coupling between Benzylic C(sp3)‒H Bond and Carboxylic Acids. CCS Chem. 2025, 10.31635/ccschem.025.202506079
Ling Dai, Ying-Ying Chen, Jing-Jun Wang, Jun-Jia Chen, Qi-Lin Zhou,* Photoinduced Copper-Catalysed Enantioselective Amination of Allylic and Propargylic C–H Bonds. Chem. Sci. 2025, 16, 9213-9219.
Yi-Cong Liu, Wen-Ao Li, Mostafa Sayed, Zhi-Yong Han,* Liu-Zhu Gong,* Photoinduced Pd-Catalyzed Carbonylative Formal [2 + 2] Cycloaddition of Alkylarenes and Imines, Org. Lett. 2025, 27, 40, 11237–11241.
Zitong Zhu, Dong Ye, Yuqiao Zhou, Weidi Cao,* Xiaoming Feng,* Photoinduced Asymmetric Dearomative Hydroalkylation of Electron-Deficient Indoles with Alkyltrifluoroborates. Org. Lett. 2025, 27, 9782−9787.
Bin Xuan, Meng-Ying Qian, Qi-Lin Zhou, Li-Jun Xiao,* Enantioselective Synthesis of γ‑Butyrolactones Bearing γ‑Quaternary Stereocenters via Nickel-Catalyzed Reductive Coupling of Acrylates with Ketones. Org. Lett. 2025, 27, 8059–8064.
Gaofei Yang, Longqing Yang, Zhenzhong Liu, Yilun Song, Yinhe Qu, Shunxi Dong,* Xiaoming Feng,* Construction of Chiral Spiro-Bridged Rings with Four Consecutive Stereocenters via Dearomative Diels–Alder Reactions of Anthracenes, Org. Lett. 2025,27, 5112–5117.
Meng-Ying Qian, Yu-Qing Wang, Qi-Lin Zhou, Li-Jun Xiao,* Nickel-Catalyzed Hydrocarbamoylation of Alkenes with Isocyanates, Organic Letters. 2025,27, 2975-2980.
Wang-Yuren Li, Longqing Yang, Xiaoxue Tang, Wenjun Yan, Zhao Wu, Fei Wang, Shunxi Dong,* Xiaoming Feng,*Asymmetric α-Selective Allylation of Amide Unit of Maleimides and Alkenyloxindoles by Dual-Functional InIII/N,N'-Dioxide Complex, Org. Chem. Front. 2025, 12, 2946−2956.
Yinhe Qu, Zhenzhong Liu, Yuqiao Zhou, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Catalytic Aziridination to Synthesize Spiro-aziridine Oxindoles, Chem. Eur. J. 2025, 31, e202500302.
Xuan-Ge Zhang, Jun-Jia Chen, Zi-Yang Zhou, Jia-Xin Li, Qi-Lin Zhou,* Enantioselective [2π + 2σ] cycloaddition of bicyclobutanes with imines: An efficient approach to chiral 2-aza-bicyclo[2.1.1]hexanes. Chem Catal. 2025, 5, 101295.10.1016/j.checat.2025.101295.
Han Yu,† Zun Yang,† Hongda Wu, Yao Luo, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Visible Light-Promoted Enantioselective Catalytic Alkylation of α-Ketoamides with Hydrocarbons, ChemCatChem 2025, 17, e202402112.
Zhongsheng Nong, Hao-Fan Qian, Chen YC, Pu-Sheng Wang,* Liuzhu Gong,* Chiral Phosphoramidite Ligand-Modulated Palladium Auto-tandem Catalysis for Asymmetric Dehydrogenative Dienylation of Imines with α-Alkenes, Sci China Chem, 2025, 68, 7, 3123 – 3129.
Fan Yang, Liuyang Pu,* Jianhua Xie,* Qi-lin Zhou, Total Synthesis of Tetracyclic Homoproaporphine Alkaloids (+)-Crociflorinone and (+)-6a-epi-Crociflorinone. Chin. J. Org. Chem. 2025, 45, 969-976.
Liang Ge, Yangbin Liu,* Xiaoming Feng,* Iron-Catalyzed Three-Component Asymmetric Carboazidation of Alkenes with Alkanes and Trimethylsilyl Azide, Synlett. 2025, 4930−4938.
Liuzhen Hou, Longqing Yang, Xiaohua Liu,* Weidi Cao,* Xiaoming Feng,* Visible-Light-Induced Enantioselective Dearomative [2+2]-Cycloaddition/Ring-Expansion Sequence of Indoles with Simple Alkenes, Synlett. 2025, 36, 944–948.
Mostafa Sayed, Xiao-Yun Ruan, Dan-Xing Wu, Zhi-Yong Han,* Liu-Zhu Gong,* Photoinduced Pd-Catalyzed Selective 1,4-Dicarbofunctionalizatio of 1,3-Butadiene with Alkyl or Aryl Bromides and Oxindoles, Synthesis, 2025, 3617–3622.
2024
Wei-Wei Ding, Zhi-Yuan He, Mostafa Sayed, Yu Zhou, Zhi-Yong Han,* Liu-Zhu Gong,* Enantioselective synthesis of β- and α-amino ketones through reversible alkane carbonylation, Nat. Synth. 2024, 3, 507−516.
Xuan-Ge Zhang, Zi-Yang Zhou, Jia-Xin Li, Jun-Jia Chen, Qi-Lin Zhou,* Copper-Catalyzed Enantioselective [4Π+2σ] Cycloaddition of Bicyclobutanes with Nitrones, J. Am. Chem. Soc. 2024, 146, 27274−27281.
Liuzhen Hou,† Longqing Yang,† Gaofei Yang, Zhe Luo, Wanlong Xiao, Linhan Yang, Fei Wang, Liu-Zhu Gong, Xiaohua Liu,* Weidi Cao,* Xiaoming Feng,* Catalytic Asymmetric Dearomative [2 + 2] Photocycloaddition/Ring-Expansion Sequence of Indoles with Diversified Alkenes, J. Am. Chem. Soc. 2024, 146, 23457–23466.
Kai-Xiang Zhang, Mei-Yu Liu, Bo-Ying Yao, Qi-Lin Zhou, Li-Jun Xiao,* Steroconvergent and Enantioselective Synthesis of Z-Homoallylic Alcohols via Nickle-Catalyzed Reductive Coupling of Z/E-1,3-Dienes with Aldehydes, J. Am. Chem. Soc. 2024, 146, 32, 22157−22165.
Ziwei Zhong, Hongda Wu, Xiaofan Chen, Yao Luo, Longqing Yang, Xiaoming Feng,* Xiaohua Liu,* Visible-Light-Promoted Enantioselective Acylation and Alkylation of Aldimines Enabled by 9-Fluorenone Electron-Shuttle Catalysis, J. Am. Chem. Soc. 2024, 146, 20401−20413.
Zhenzhong Liu,† Hongli Wu,† Helong Zhang, Fang Wang, Xiaohua Liu, Shunxi Dong,* Xin Hong,* Xiaoming Feng,* Iron-Catalyzed Asymmetric Imidation of Sulfides via Sterically Biased Nitrene Transfer, J. Am. Chem. Soc. 2024, 146, 18050–18060.
Zhi-Hong Chen, Li-Jie Gu, Biao Wang*, Li-Jun Xiao,* Meng-Chun Ye, Qi-Lin Zhou,* Regioselective and Enantioselective Nickle-Catalyzed Intermolecular Reductive Coupling of Aliphatic Alkenes with Imines. J. Am. Chem. Soc. 2024. 146, 14915−14921.
Liang Ge, Hongkai Wang, Yangbin Liu,* Xiaoming Feng,* Asymmetric Three-Component Radical Alkene Carboazidation by Direct Activation of Aliphatic C−H Bonds, J. Am. Chem. Soc. 2024, 146, 13347−13355.
Ai-Cui Han, Li-Jun Xiao, Qi-Lin Zhou,* Construction of Ge-Stereogenic Center by Desymmetric Carbene Insertion of Dihydrogermanes, J. Am. Chem. Soc. 2024, 146, 5643−5649.
Tianze Zhang, Shan Jiang, Meng-Ying Qian, Qi-Lin Zhou, Li-Jun Xiao,* Ligand-Controlled Regiodivergent Nickle-Catalyzed Hydroaminoalkylation of Unactivated Alkenes, J. Am. Chem. Soc. 2024, 146, 3458−3470.
Xiao-Yun Ruan, Xiao-Yun Ruan, Dan-Xing Wu, Wen-Ao Li, Zihan Lin, Mostafa Sayed, Zhi-Yong Han,* Liu-Zhu Gong,* Photoinduced Pd-Catalyzed Enantioselective Carboamination of Dienes via Aliphatic C–H Bond Elaboration, J. Am. Chem. Soc. 2024, 146, 12053−12062.
Haorui Wang, Jiang-Fei Li, Mengying Xu, Qi-Lin Zhou, Weiwei Xu,* Mengchun Ye,* Enantioselective Construction of Oxindoles Bearing a Quaternary Carbon via Ni–Al Bimetal-Catalyzed Formyl C–H Alkylation, Angew. Chem. Int. Ed. 2024, e202413652.
Zhijie Xiao,† Maoping Pu,† Yuzhen Li, Wei Yang, Fei Wang, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Catalytic Synthesis of Allylic Sulfenamides from Vinyl α-Diazo Compounds by a Rearrangement Route, Angew. Chem. Int. Ed. 2024, 63, e202414712.
Wen-Yao Wang, Jing-Jun Wang, Jia-Bin Pan, Li-Jun Xiao, Qi-Lin Zhou,* Enantioselective reductive C-O bond cleavage driven by photoinduced electron transfer. Chem. 2024, 10.1016/j.chempr.2024.08.002
Yi Li, Yu-Peng Liu, Mengying Xu, Weiwei Xu, Feng-Ping Zhang ,* Mengchun Ye,* Ni-Al Bimetal-Catalyzed Tertiary C(sp3)-H Activation for Dual C-H Annulation of Formamides with Alkynes, CCS Chem. 6, 2671−2678.
Zheng Wang, Xin-Yi Yang, Yue Xu, Qi-Lin Zhou,* Iridium-catalyzed Asymmetric Hydrogenation of Dialkyl Imines, CCS Chem. 2024, 6, 905−911.
Yazhou Lou, Zihan Lin, Chenxi Wu, Zhong-Sheng Nong, Rui Liu, Liu-Zhu Gong,* Enantioselective Synthesis of Chiral 1,4-Enynes via Palladium-Catalyzed Branch-Selective Allylic C−H Alkylation, ACS Catal. 2024, 14, 14855−14862.
Yao Luo, Yuqiao Zhou, Fengnan Xiao, Xin He, Ziwei Zhong, Qi-Lin Zhou, Weidi Cao,* Xiaohua Liu,* Xiaoming Feng,* Quinone-Initiated Photocatalytic Enantioselective Giese Radical Addition with Ethers, Thioethers, Amines and Alkanes, ACS Catal. 2024, 14, 12031−12041.
Yuhao Mo, Lichao Ning, Zhe Luo, Liangkun Yang, Shi Tang, Shunxi Dong*, Qi-Lin Zhou, Xiaoming Feng,* Asymmetric Photoenolization/Diels−Alder Reaction of 2‑Methylbenzaldehydes and 2‑Alkylbenzophenones with Chromones, ACS Catal. 2024, 14, 6687−6695.
Xuan-Ge Zhang, Zhi-Chun Yang, Jia-Bin Pan, Xiao-Hua Liu, Qi-Lin Zhou,* Enantioselective synthesis of chiral amides by carbene insertion into amide N-H bond, Nat. Commun. 2024, 15, 4793−4801.
Ai-Cui Han, Xuan-Ge Zhang, Liang-Liang Yang, Jia-Bin Pan, Hui-Na Zou, Mao-Lin Li, Li-Jun Xiao, Qi-Lin Zhou,* Rhodium-catalyzed Enantioselective C-Ge Bond Formation by Carbene Insertion: An Efficient Access to Chiral Organogermanes, Chem. Catal. 2024. 4, 100890−100904.
Lei Zhang, Mengfan Li, Yin Yang, Xu Cheng,* Qi-Lin Zhou,* Electrochemical reduction of benzoic acid esters using water as a H/D source, Green Chem., 2024, 26, 2059−2066.
Shuang Xin, Jibang Liao, Qi Tang, Xiaoming Feng, Xiaohua Liu,* Photoinduced Copper-Catalyzed Asymmetric Cyanoalkylalkynylation of Alkenes, Terminal Alkyne, and Oximes, Chem. Sci. 2024, 15, 10.1039/D4SC05642F
Jiuqi Tan, Longqing Yang, Hanyu Su, Yuntian Yang, Ziwei Zhong, Xiaoming Feng,* Xiaohua Liu,* Visible-Light-Driven Asymmetric Aldol Reaction of Ketones and Glycinates via Synergistic Lewis Acid/Photoredox Catalysis, Chem. Sci. 2024, 15, 16050–16058.
Zhenwei Wu,† Xi Yang,† Fangqing Zhang, Yangbin Liu,* Xiaoming Feng,* Tandem Catalytic Allylic C–H Amination and Asymmetric [2,3]-Rearrangement via Bimetallic Relay Catalysis, Chem. Sci. 2024, 15, 13299–13305.
Tangyu Zhan, Liang Zhou, Yuqiao Zhou, Bingqian Yang, Xiaoming Feng,* Xiaohua Liu,* IronIII-Catalyzed Asymmetric Inverse-Electrondemand Hetero-Diels–Alder Reaction of Dioxopyrrolidines with Simple Olefins, Chem. Sci. 2024, 15, 4797−4803.
Aying Yihuo, Maoping Pu, Zheng Tan, Jibang Liao, Jiuqi Tan, Qilin Zhou, Xiaohua Liu,* Xiaoming Feng,* Copper-Catalyzed Asymmetric Dearomatizing Amination of 2-Naphthols: C(sp2)-N Coupling via 1,3-Reductive Elimination, Sci. China Chem. 2024, 67, 2694−2700.
Dongyi Cao,† Ruiying Xi,† Hongye Li,† Zhonghui Zhang, Xiaoke Shi, Shanshan Li, Yujie Jin, Wanli Liu, Guolin Zhang, Xiaohua Liu, Shunxi Dong, * Xiaoming Feng,* Fei Wang,* Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation and Pyroptosis, J. Med. Chem. 2024, 67, 15873–15891.
Zhong-Sheng Nong, Pu-Sheng Wang,* Qi-Lin Zhou,* Liu-Zhu Gong,* Palladium-Catalyzed Branch-Selective Allylic C−H Amination Enabled by Nucleophile Coordination, Org. Lett. 2024, 26, 8481−8485
Siyuan Wang, Lichao Ning, Zhiqiang Li, Xiaoming Feng*, Xiaohua Liu* Asymmetric Synthesis of Hydrodibenzofurans from Norcaradienes: Kinetic Resolutionvia [3 + 2] Cycloaddition with Quinones, Org. Lett. 2024, 26, 3844−3849.
Xiao-Yun Ruan, Dan-Xing Wu, Wen-Ao Li, Zihan Lin, Mostafa Sayed, Zhi-Yong Han,* Liu-Zhu Gong,* Photoinduced Decatungstate Anion-Catalyzed 1,4-Difunctionalization of 1,3-Butadienes via C–H Activation, Org. Lett. 2024, 26, 5528–5533.
Zun Yang, Zheng Jiang, Zheng Tan, Han Yu, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Catalytic Concise Synthesis of 3-(3-Indolomethyl)-oxindoles for the Construction of Trigolute Analogs, Chem. Commun. 2024, 60, 10926−10929.
Zheng Tan, Aying Yihuo, Zhao Wu, Fei Wang, Shunxi Dong,* Xiaoming Feng,* Concise synthesis of chiral γ-butenolides via an allylation/lactonization cascade reaction, Chem. Commun. 2024, 60, 7926−7929.
Hongkun Zeng, Gang Wen, Lili Lin,* Xiaoming Feng,* Asymmetric Dearomatization of Benzyl 1-Naphthyl Ethers via [1,3] O-to-C Rearrangement, Chem. Commun. 2024, 60, 7507−7510.
Hongye Li, Yuqiao Zhou, Zheng Tan, Xiangyu Wang, Yuxin Zhang, Fei Wang, Xiaoming Feng,* Xiaohua Liu,* Enantioselective sulfonylation to construct 3-sulfonylated oxindoles, Chem. Commun. 2024, 60, 4354−4357.
Zhenda Tan, Yangbin Liu,* Xiaoming Feng,* Photoredox-catalyzed C(sp3)−H radical functionalization to enable asymmetric synthesis of α-chiral alkyl phosphine, Sci. Adv. 2024, 10, eadn9738.
Neng-Quan Jiang,† Ming-Ming Li,† Li-Jun Xiao,* Qi-Lin Zhou,* Nickle-Catalyzed Enantioselective α-Allylation of Cyclic Ketones with Allylic Alcohols. Adv. Synth. Catal. 2024, 366, 3829−3832.
Liang Ge, Yangbin Liu,* Xiaoming Feng,* Iron-Catalyzed Three-Component Asymmetric Carboazidation of Alkenes with Alkanes and Trimethylsilyl Azide, Synlett. 2024, 10.1055/a-2352-4835
2023
Fan Yang, Jian-Hua Xie,* Qi-Lin Zhou,* Highly Efficient Asymmetric Hydrogenation Catalyzed by Iridium Complexes with Tridentate Chiral Spiro Aminophosphine Ligands. Acc. Chem. Res. 2023, 56, 332−349.
Dong Zhang,† Maoping Pu,† Zhenzhong Liu, Yuqiao Zhou, Zhendong Yang, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Enantioselective anti-Dihalogenation of Electron-Deficient Olefin: A Triplet Halo-Radical Pylon Intermediate, J. Am. Chem. Soc. 2023, 145, 4808−4818.
Qianwen He,† Mao-Ping Pu,† Zheng Jiang, Hongyu Wang, Xiaoming Feng,* Xiaohua Liu,* Asymmetric Epoxidation of Alkenes Catalyzed by a Cobalt Complex, J. Am. Chem. Soc. 2023, 145, 15611−15618.
Jin-Tao Ma, Tianze Zhang, Bo-Ying Yao, Li-Jun Xiao,* Qi-Lin Zhou, Diastereodivergent and Enantioselective Synthesis of Homoallylic Alcohols via Nickel-Catalyzed Borylative Coupling of 1,3-Dienes with Aldehydes. J. Am. Chem. Soc. 2023, 145, 19195−19201.
Youxiang Jin, Lian-Feng Fan, Elvis Wang Hei Ng, Lu Yu, Hajime Hirao,* Liu-Zhu Gong,* Atom Transfer Radical Coupling Enables Highly Enantioselective Carbo-Oxygenation of Alkenes with Hydrocarbons, J. Am. Chem. Soc. 2023, 145, 40, 22031–22040.
Zheng Tan, Long Chen, Lingyu Li, Yuzhen Li, Yao Luo, Fei Wang, Shunxi Dong,* Xiaoming Feng,* Asymmetric Synthesis of α-Methylene-γ-butyrolactones via Tandem Allylboration/Lactonization: a Kinetic Resolution Process, Angew. Chem. Int. Ed. 2023, 62, e202306146.
Ling Dai, Ying-Ying Chen, Li-Jun Xiao, Qi-Lin Zhou,* Intermolecular Enantioselective Benzylic C(sp3)–H Amination by Cationic Copper Catalysis. Angew. Chem. Int. Ed. 2023, 62, e202304427.
Jia-Bin Pan, Zhi-Chun Yang, Xuan-Ge Zhang, Mao-Lin Li, Qi-Lin Zhou,* Enantioselective Synthesis of Chiral Amides by a Phosphoric Acid Catalyzed Asymmetric Wolff Rearrangement. Angew. Chem. Int. Ed. 2023, 62, e202308122.
Jia-Bin Pan, Xuan-Ge Zhang, Yi-Fan Shi, Ai-Cui Han, Yu-Jia Chen, Jing Ouyang, Mao-Lin Li,* Qi-Lin Zhou,* A Spiro Phosphamide Catalyzed Enantioselective Proton Transfer of Ylides in a Free Carbene Insertion into N–H Bonds. Angew. Chem. Int. Ed. 2023, 62, e202300691.
Zhong-Sheng Nong, Xin-Ran Chen, Pu-Sheng Wang,* Xin Hong,* Liu-Zhu Gong,* Enantioconvergent Palladium-Catalyzed Alkylation of Tertiary Allylic C−H Bonds, Angew. Chem. Int. Ed. 2023, 62, e20231254.
Rui Liu, Meng-Lan Shen, Lian-Feng Fan, Xiao-Le Zhou, Pu-Sheng Wang,* Liu-Zhu Gong,* Palladium-Catalyzed Branch- and Z-Selective Allylic C−H Amination with Aromatic Amines, Angew. Chem. Int. Ed. 2023, 62, e202211631.
Feng-Ping Zhang, Rong-Hua Wang, Jiang-Fei Li, Hao Chen,* Madala Hari Babu,* Mengchun Ye,* Intermolecular Carbophosphination of Alkynes with Phosphole Oxides via Ni–Al Bimetal-Catalyzed C–P Bond Activation, Angew. Chem. Int. Ed. 2023, 62, e202314701.
Ming-Ming Li, Tianze Zhang, Lei Cheng, Wei-Guo Xiao, Jin-Tao Ma, Li-Jun Xiao,* Qi-Lin Zhou,* Ketone α-Alkylation at the More-Hindered Site. Nat. Commun. 2023, 14, 3326.
Shunxi Dong, Weidi Cao, Maoping Pu, Xiaohua Liu,* Xiaoming Feng,* Ligand-Acceleration in Chiral Lewis Acid Catalysis, CCS Chem. 2023, 5, 2717−2735
Tangyu Zhan, Liangkun Yang, Qiyou Chen, Rui Weng, Xiaohua Liu,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Norrish Type II Cyclization to Synthesize α-Oxazolidinones via Enantioselective Protonation, CCS Chem. 2023, 5, 2101–2110.
Biao Wang, Xian-Ming Liu, Kai-Xiang Zhang, Wei-Min Feng, Li-Jun Xiao,* Qi-Lin Zhou,* Diastereoselective and Enantioselective Nickel-Catalyzed Reductive Coupling of Imines and Unactivated Alkenes. CCS Chem. 2023, 5, 814–822.
Zhikun Wu,† Xiying Zhang,† Nian Xu, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Aerobic Oxidative Radical Addition/Hydroxylation/1,4-Aryl Migration Reaction of Olefins, ACS Catal. 2023, 13, 815−823.
Biao Wang, Tianze Zhang, Li-Jun Xiao,* Qi-Lin Zhou,* Nickel-Catalyzed Intermolecular Reductive Coupling of Styrene and Its Derivatives with Imines Using Methanol as a Reductant. ACS Catal. 2023, 13, 8692−8699.
Siyuan Wang, Yuqiao Zhou, Wanlong Xiao, Zegong Li, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Synthesis of Complex Tricyclo[3.2.2.0]nonenes from Racemic Norcaradienes: Kinetic Resolution via Diels–Alder Reaction, Chem. Sci. 2023, 14, 1844−1851.
Lili Feng, Xiaofan Chen, Ning Guo, Yuqiao Zhou, Lili Lin, Weidi Cao,* Xiaoming Feng,* Visible-Light-Induced Chemo-, Diastereo- and Enantioselective α-C(sp3)−H Functionalization of Alkyl Silanes, Chem. Sci. 2023, 14, 4516−4522.
Wei-Guo Xiao, Bin Xuan, Li-Jun Xiao,* Qi-Lin Zhou, Practical Synthesis of Allylic Amines via Nickel-Catalysed Multicomponent Coupling of Alkenes, Aldehydes, and Amides. Chem. Sci. 2023, 14, 8644–8650.
Zi-Jian Liu, Jiang-Fei Li, Feng-Ping Zhang, Xue-Tao Xu,* Mengchun Ye,* Catalyst-Controlled Nickel-Catalyzed Intramolecular endo-Selective C−H Cyclization of Benzimidazoles with Alkenes, Org. Lett. 2023, 25, 353-357.
Mingzhen Lu, Weiwei Xu, Mengchun Ye,* Phosphine Oxide-Promoted Rh(I)-Catalyzed C–H Cyclization of Benzimidazoles with Alkenes, Molecules 2023, 28, 736-745.
Chenhao Zhu, Yuqiao Zhou, Jia Yang, Xiaoming Feng, Shunxi Dong,* Lanthanide-catalyzed Regio- and Enantioselective Hydrosilylation of Aryl-substituted Terminal and Internal Alkenes, Org. Chem. Front. 2023, 10, 1263–1269.
Tinghui Zhang, Ziwei Zhong, Zi Zeng, Zitong Zhu, Fei Wang, Yuxin Zhang, Xiaohua Liu, Maoping Pu,* Xiaoming Feng,* Asymmetric Catalytic Friedel–Crafts Alkylation with Arenes and Heteroarenes: Construction of 3,3-Disubstituted Oxindoles, Org. Chem. Front. 2023, 10, 5274–5283.
Wei Yang, Zhendong Yang, Long Chen, Yican Lu, Cefei Zhang, Zhishan Su, Xiaohua Liu,* Xiaoming Feng,* Chiral Nickel(II) Complex Catalyzed Asymmetric (3 + 2) Cycloaddition of α-Diazo Pyrazoleamides with 2-Siloxy-1-alkenes, Chin. Chem. Lett. 2023, 33, 107791.
Jia-Hui Wei,† You-Xiang Jin,† Pu-Sheng Wang,* Liu-Zhu Gong,* Access to Fluorinated Quaternary Stereogenic Centers via Palladium-Catalyzed Asymmetric Allylic C–H Alkylation, Synlett 2023, 34, A–F.
Lili Lin, Yuqiao Zhou, Weidi Cao, Shunxi Dong, Xiaohua Liu, Xiaoming Feng,* Progress in N,N′-Dioxide/metal Complex-catalyzed Asymmetric Reactions of Ylides, Sci. Sin. Chem. 2023, 53, 246−258.
Pu-Sheng Wang, Liu-Zhu Gong,* Pd-Catalyzed Asymmetric Allylic C-H Functionalization, Chin. J. Chem. 2023, 41, 1841–1848.
2022
Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Rearrangements with α‑Diazocarbonyl Compounds, Acc. Chem. Res. 2022, 55, 415−428.
Jiang-Fei Li, Deng Pan, Hao-Rui Wang, Tao Zhang, Yi Li, Genping Huang,* Mengchun Ye,* Enantioselective C2−H Alkylation of Pyridines with 1,3-Dienes via Ni−Al Bimetallic Catalysis. J. Am. Chem. Soc. 2022, 144, 18810–18816.
Wanlong Xiao, Lichao Ning, Shuang Xin, Shunxi Dong, Xiaohua Liu,* Xiaoming Feng,* Enantioselective[2+2] Cycloaddition of Allenyl Imidewith Mono-, or Disubstituted Alkenes, Angew. Chem. Int. Ed. 2022, 61, e202211596.
Lifeng Wang, Yuqiao Zhou, Zhishan Su, Fengcai Zhang, Weidi Cao, Xiaohua Liu,* Xiaoming Feng,* [3,3]-Sigmatropic Rearrangements of Naphthyl 1-Propargyl Ethers: para-Propargylation and CatalyticAsymmetricDearomatization, Angew. Chem. Int. Ed. 2022, 61, e202211785.
Xiaobin Lin,† Maoping Pu,† Xinpeng Sang, Shiyang Li, Xiaohua Liu,* Yun-Dong Wu,* Xiaoming Feng,* Asymmetric Catalytic (2+1) Cycloaddition of Thioketones to Synthesize Tetrasubstituted Thiiranes, Angew. Chem. Int. Ed. 2022, 61, e202201151.
Qianchi Lin, Sujuan Zheng, Long Chen, Jin Wu, Jinzhao Li, Peizhi Liu, Shunxi Dong,* Xiaohua Liu, Qian Peng,* Xiaoming Feng,* Catalytic Regio- and Enantioselective Protonation for the Synthesis of Chiral Allenes: Synergistic Effect of the Counterion and Water, Angew. Chem. Int. Ed. 2022, 61, e202203650.
Zhenda Tan, Shibo Zhu, Yangbin Liu,* Xiaoming Feng,* Photoinduced Chemo-, Site- and Stereoselective α-C(sp3)−H Functionalization of Sulfides, Angew. Chem. Int. Ed. 2022, 61, e202203374.
Tian-Yuan Zhao, Li-Jun Xiao, Qi-Lin Zhou,* Nickel-Catalyzed Desymmetric Reductive Cyclization/Coupling of 1,6-Dienes: An Enantioselective Approach to Chiral Tertiary Alcohol. Angew. Chem. Int. Ed. 2022, 61, e202115702.
Yin-Xia Wang, Feng-Ping Zhang, Hao Chen, Yue Li, Jiang-Fei Li, Mengchun Ye,* Enantioselective Nickel-Catalyzed C(sp3)-H Activation of Formamides. Angew. Chem. Int. Ed. 2022, 61, e202209625.
Zhong-Sheng Nong, Ling Zhu, Tian-Ci Wang, Lian-Feng Fan, Pu-Sheng Wang,* Liu-Zhu Gong,* Palladium-catalysed branch- and enantioselective allylic C–H alkylation of α-alkenes, Nat. Synth. 2022, 1, 487–496.
Lian-Feng Fan, Rui Liu, Xiao-Yun Ruan, Pu-Sheng Wang, Liu-Zhu Gong,* Asymmetric 1,2-oxidative alkylation of conjugated dienes via aliphatic C−H bond activation, Nat. Synth. 2022, 1, 946-955.
Shao-Long Qi, Yu-Peng Liu, Yu-Xin Luan, Mengchun Ye,* Ni-catalyzed hydroarylation of alkynes with unactivated b-C(sp2)−H bonds. Nat. Comm. 2022, 13, 2938-2946.
Rong-Hua Wang, Wei-Wei Xu, Hongli Wu, Yue Li, Jiang-Fei Li, Tao Zhang, Genping Huang,* Mengchun Ye,* Ni-catalyzed benzylic β-C(sp3)–H bond activation of formamides. Nat. Comm. 2022, 13, 7892-7900.
Tangyu Zhan, Liangkun Yang, Qiyou Chen, Rui Weng, Xiaohua Liu,* Xiaoming Feng,* Chiral Lewis Acid-Catalyzed Norrish Type II Cyclization to Synthesize α-Oxazolidinones via Enantioselective Protonation, CCS Chem. 2022, 4, 10.31635/ccschem.022.202202405
Biao Wang, Xian-Ming Liu, Kai-Xiang Zhang, Wei-Min Feng, Li-Jun Xiao,* Qi-Lin Zhou,* Diastereoselective and Enantioselective Nickel-Catalyzed Reductive Coupling of Imines and Unactivated Alkenes. CCS Chem. 2022, 4, DOI: 10.31635/ccschem.022.202202506.
Xiao-Yun Ruan, Tao Zhang, Wen-Ao Li, Yi-Zhuo Yin, Zhi-Yong Han,* Liu-Zhu Gong,* Photoinduced and Palladium-Catalyzed Hydrogen Atom Transfer Triggered 1,2-Difunctionalization of 1,3-Dienes with Hydroxamides, Sci. China Chem. 2022, 65, 863-869.
Han Yu, Tangyu Zhan, Yuqiao Zhou, Long Chen, Xiaohua Liu,* Xiaoming Feng,* Visible-Light-Activated Asymmetric Addition of Hydrocarbons to Pyridine-Based Ketones, ACS Catal. 2022, 12, 5136−5144.
Zhikun Wu,† Xiying Zhang,† Nian Xu, Xiaohua Liu,* Xiaoming Feng,* Asymmetric Catalytic Aerobic Oxidative Radical Addition/Hydroxylation/1,4-Aryl Migration Reaction of Olefins, ACS Catal. 2023, 13, 815−823.
Youxiang Jin,† Elvis Wang Hei Ng,† Tao Fan, Hajime Hirao,* Liu-Zhu Gong,* Photochemical Allylation of Alkanes Enabled by Nickel Catalysis, ACS Catal. 2022, 12, 10039.
Liangkun Yang, Wang-Yuren Li, Liuzhen Hou, Tangyu Zhan, Weidi Cao,* Xiaohua Liu, Xiaoming Feng,* NickelⅡ-Catalyzed Asymmetric Photoenolization/Mannich Reaction of (2-Alkylphenyl) Ketones, Chem. Sci. 2022, 13, 8576–8582.
Yangbin Liu, Xiaohua Liu,* Xiaoming Feng,* Recent Advances in Metal-Catalysed Asymmetric Sigmatropic Rearrangements, Chem. Sci. 2022, 13, 12290–12308.
Wen-Qian Zhang, Hong-Cheng Shen, Liu-Zhu Gong,* Dearomative Arylcyanation of Indoles via C–CN Bond Activation Enabled by Ni/Lewis Acid Cooperative Catalysis, Org. Lett. 2022, 24, 6637-664.
Yu-Xin Luan, Mengchun Ye,* Ligand-ligated Ni–Al bimetallic catalysis for C–H and C–C bond activation. Chem. Commun. 2022, 58, 12260-12273.
Jinzhao Li, Lichao Ning, Qingfa Tan, Xiaoming Feng, Xiaohua Liu,* Asymmetric Sonogashira C(sp3 )-C(sp) Bond Coupling Enabled by Copper(I) Complex of New Guanidine-Hybrid Ligand, Org. Chem. Front. 2022, 9, 6312−6318.
Wei-Min Feng, Xian-Ming Liu, Li-Jun Xiao,* Qi-Lin Zhou,* Synthesis of Tricyclic [1,2-a]Indoles via Nickel-Catalyzed Intramolecular Imine-Alkene Coupling. Adv. Synth. Catal. 2022, 364, 3420–3423.
Dong-Yang Zhang，Liu-Zhu Gong,* Enantioselective Oxidative Dearomatization of 2-NaphtholsEnabled by Chiral Organoiodine Catalysis, Synlett 2022, 33, 10.1055/s-0042-1751351
Wei Yang, Zhendong Yang, Long Chen, Yican Lu, Cefei Zhang, Zhishan Su, Xiaohua Liu,* Xiaoming Feng,* Chiral Nickel(II) Complex Catalyzed Asymmetric (3 + 2) Cycloaddition of α-Diazo Pyrazoleamides with 2-Siloxy-1-alkenes, Chin. Chem. Lett. 2022, 32, 10.1016/j.cclet.2022.107791
Weiwei Xu, Mengchun Ye,* Enantioselective Cobalt-Catalyzed C–H Functionalization. Synthesis 2022, 54, 4773–4783.
Xiao-Ya Sun, Bo-Ying Yao, Bin Xuan, Li-Jun Xiao,* Qi-Lin Zhou,* Recent Advances in Nickel-Catalyzed Asymmetric Hydrofunctionalization of Alkenes. Chem Catal. 2022, 2, 3140–3162.
Haorui Wang, Mengchun Ye,* Research Advance on Enantioselective Transition Metal-Catalyzed Hydroacylation Reactions. Chin. J. Org. Chem. 2022, 42, 3152–3166.
Patents
一种联萘胺衍生的手性膦氧配体促进的镍催化Csp3-H不对称环化，申请号：202210964711.5，申请日：2022年08月12日，发明人 : 叶萌春、王银霞、张凤萍
一种二胺衍生的膦手性膦氧配体促进的镍催化吡啶C2-H键不对称烷基化，申请号：202211179758.7，申请日：2022年09月27日，发明人 : 叶萌春、李江飞
一种不对称催化合成手性1,4-二氢吡啶化合物的方法及其应用，申请号：202210586317，申请日：2022年05月27日，发明人 : 冯小明、胡欣月、刘小华、陈龙、曹伟地、董顺喜
